Catherine and I tried out acrylic craft paint on our nails this last Saturday, our spa day. I had Liquitex gloss sealant, mica dust and some water transfer nail decals, Catherine brought the paint. We did each other's right hand, so my nails on my left hand were finished differently than my right. Catherine applied fewer coats of sealant and didn't use any decals. The paint looked good when finished and if I'd been doing a special occasion/event, it would have lasted 24 hours easy. Catherine commented that it held up as well as the vinyl nail wraps she'd been using. I did the dishes, wearing gloves, Sunday. That destroyed my right nails, but the nails on my left hand did much better. After 3 sinks full of dishes in high heat water, all but my thumb nail with the decal were damaged. By Monday afternoon my thumbnail was starting to peel. I think the decal helped the paint to last. I'm very rough on my hands, so I think the acrylic paint did very well. While the acrylic paint is not entirely safe, it doesn't have all the off gassing of traditional nail polish. Catherine and I didn't have any obvious adverse reactions. I don't think I'll be doing this all the time, but maybe once in a great while.